R-360163 |CAS:883791-50-2 Probechem Biochemicals

Chemical Structure : R-360163

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R-360163 (R360163)

货号: PC-61807Not For Human Use, Lab Use Only.

R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.

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生物&药学活性

R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay.
R-360163 displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

物理化学性质&存储条件

分子量	392.371
分子式	C20H16N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-3-(2-(2-(1-allyl-2-oxoindolin-3-ylidene)hydrazinyl)-2-oxoacetamido)benzoic acid

参考文献

1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11.

R-360163 (R360163)

生物&药学活性

物理化学性质&存储条件

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R-360163 (R360163)

生物&药学活性

物理化学性质&存储条件

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