Quinobene |CAS:140942-13-8 Probechem Biochemicals

Chemical Structure : Quinobene

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Quinobene

货号: PC-61258Not For Human Use, Lab Use Only.

Quinobene is a HIV-1 surface-membrane inhibitor, also is a Fap1-blocking small molecule that replicates SLV peptied functions.

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生物&药学活性

Quinobene is a HIV-1 surface-membrane inhibitor, also is a Fap1-blocking small molecule that replicates SLV peptied functions.
Quinobene blocks co-immunoprecipitation of Fas or Apc with Fap1, decreases β-catenin and survivin in Bcr-abl+ murine bone marrow cells.
Quinobene does not alter Fap1-independent Bcr-abl targets, impairs Bcr-abl+ cell outgrowth.

物理化学性质&存储条件

分子量	930.723
分子式	C32H18N6Na4O14S4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(7E)-8-oxo-7-[[4-[(Z)-2-[4-[(2E)-2-(8-oxo-5-sulfonatoquinolin-7-ylidene)hydrazinyl]-2-sulfonatophenyl]ethenyl]-3-sulfonatophenyl]hydrazinylidene]quinoline-5-sulfonate tetrasodium

参考文献

1. Gruszecka-Kowalik E, et al. Biochem Biophys Res Commun. 1992 Sep 30;187(3):1409-17.

2. Tobin GJ, et al. Antiviral Res. 1996 Dec;33(1):21-31.

3. Huang W, et al. Leukemia. 2016 Jul;30(7):1502-9.

Quinobene

生物&药学活性

物理化学性质&存储条件

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Quinobene

生物&药学活性

物理化学性质&存储条件

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