Quin-C1 (Quin C1)

Chemical Structure : Quin-C1

CAS No.: 786706-21-6

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货号: PC-20393Not For Human Use, Lab Use Only.

Quin C1 is a potent and selective FPR2 agonist with EC50 of 15 nM, induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells.

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5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3980	In stock
50 mg	￥5980	In stock
100 mg		Get quote

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生物&药学活性

Quin C1 is a potent and selective FPR2 agonist with EC50 of 15 nM, induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells.
Quin C1 induces neutrophil chemotaxis and degranulation in vitro.
Quin C1 reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model.
Quin C1 exhibits anti-inflammatory property in a mouse model of bleomycin-induced lung injury.

物理化学性质&存储条件

分子量	445.52
分子式	C26H27N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide

参考文献

1. Nanamori M et al. Mol. Pharmacol, 2004, 66, 1213–1222.

2. Min He, et al. Acta Pharmacol Sin. 2011 May;32(5):601-10.

Quin-C1 (Quin C1)

生物&药学活性

物理化学性质&存储条件

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Quin-C1 (Quin C1)

生物&药学活性

物理化学性质&存储条件

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