Chemical Structure : QDPR inhibitor 9b
CAS No.: 29415-71-2
货号: PC-22340Not For Human Use, Lab Use Only.
QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM.
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QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM.
Treatment with QDPR inhibitor 9b combined with methotrexate (MTX), an inhibitor of another BH4-reducing enzyme, dihydrofolate reductase (DHFR), significantly oxidized intracellular redox states in HepG2, Jurkat, SH-SY5Y, and PC12D cells.
分子量 | 233.27 | |
分子式 | C12H15N3O2 | |
外观性状 | Solid | |
储存条件 |
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|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
6-(diethylamino)-2,3-dihydrophthalazine-1,4-dione |
1. Satoshi Hara, et al. Biochem Biophys Res Commun. 2024 May 4:717:150059.
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