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Q151

Chemical Structure : Q151

CAS No.: 2226449-95-0

Q151 (Mtb IMPDH2 inhibitor, Q-151)

货号: PC-35157Not For Human Use, Lab Use Only.

Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (Mtb IMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Q151 is a highly potent inhibitor of mycobacterium tuberculosis IMPDH2 (Mtb IMPDH2) with Kiapp of 18 nM, demonstrates the minimum inhibitory concentrations (MIC) of 1 uM withour significant cytotoxicity.

    物理化学性质&存储条件

    分子量 418.404
    分子式 C23H16F2N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-N-(2-(4-Cyanophenyl)benzo[d]oxazol-5-yl)-2-((2,3-difluorophenyl)amino)propanamide

    参考文献

    1. Chacko S, et al. J Med Chem. 2018 May 30. doi: 10.1021/acs.jmedchem.7b01839.

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