Pyruvate Carboxylase-IN-5 | Pyruvate carboxylase inhibitor

Chemical Structure : Pyruvate Carboxylase-IN-5

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Pyruvate Carboxylase-IN-5 (Compound 6m)

货号: PC-27058Not For Human Use, Lab Use Only.

Pyruvate Carboxylase-IN-5 (Compound 6m) is a selective pyruvate carboxylase (PC) inhibitor with IC50 of 3.4 uM.

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生物&药学活性

Pyruvate Carboxylase-IN-5 (Compound 6m) is a selective pyruvate carboxylase (PC) inhibitor with IC50 of 3.4 uM.
Pyruvate Carboxylase-IN-5 does not inhibit the metalloenzymes human carbonic anhydrase II and matrix metalloprotease-12, does not inhibit the related biotin-dependent enzyme, guanidine carboxylase.

物理化学性质&存储条件

分子量	294.24
分子式	C13H11FN2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl 2-(3-(4-fluorophenyl)-2,4,5-trioxoimidazolidin-1-yl)acetate

参考文献

1. Nicholas O Schneider, et al. ACS Med Chem Lett. 2024 Jun 26;15(7):1088-1093.

Pyruvate Carboxylase-IN-5 (Compound 6m)

生物&药学活性

物理化学性质&存储条件

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Pyruvate Carboxylase-IN-5 (Compound 6m)

生物&药学活性

物理化学性质&存储条件

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