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首页-小分子抑制剂&激动剂-Others-Other Targets-Pyruvate Carboxylase-IN-1
Pyruvate Carboxylase-IN-1

Chemical Structure : Pyruvate Carboxylase-IN-1

CAS No.: 70205-50-4

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Pyruvate Carboxylase-IN-1

货号: PC-27059Not For Human Use, Lab Use Only.

Pyruvate Carboxylase-IN-1 (Compound 37) is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 204 nM and 104 nM for PC in cell lysates and cells, shows antiproliferative activity against human hepatocellular carcinoma (HCC).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Pyruvate Carboxylase-IN-1 (Compound 37) is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 204 nM and 104 nM for PC in cell lysates and cells, shows antiproliferative activity against human hepatocellular carcinoma (HCC).

物理化学性质&存储条件

分子量 242.27
分子式 C15H14O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Methoxy-9,10-dihydrophenanthrene-4,5-diol

参考文献

1. Yuwen Sheng, et al. J Med Chem. 2022 Jan 13;65(1):460-484.

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