Pyridoxal Isonicotinoyl Hydrazone

Chemical Structure : Pyridoxal Isonicotinoyl Hydrazone

CAS No.: 737-86-0

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货号: PC-27602Not For Human Use, Lab Use Only.

Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions.

规格	价格	库存
10 mg	￥480	In stock
25 mg	￥780	In stock
50 mg	￥1180	In stock
100 mg		Get quote

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生物&药学活性

Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions.

物理化学性质&存储条件

分子量	286.29
分子式	C14H14N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide

参考文献

1. Ponka P, et al. Blood. 1985 Apr;65(4):850-7.

2. Hermes-Lima M, et al. Biochim Biophys Acta. 2000 Oct 18;1523(2-3):154-60.

3. Landschulz W, et al. J Cell Biol. 1984 Feb;98(2):596-601.