Pyk2-IN-25a |CAS:2052970-45-1 Probechem Biochemicals

Chemical Structure : Pyk2-IN-25a

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Pyk2-IN-25a

货号: PC-62798Not For Human Use, Lab Use Only.

Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM).

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生物&药学活性

Pyk2-IN-25a is a highly potent Pyk2 (PTK2B) inhibitor with IC50 of 0.67 nM, dispalys 2-fold weakening potency for FAK (IC50=1.26 nM).
Pyk2-IN-25a is a suitable tool compound for future proof-of-concept studies.

物理化学性质&存储条件

分子量	478.494
分子式	C21H21F3N6O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	7-(methylsulfonyl)-35-(trifluoromethyl)-2,4,7-triaza-3(2,4)-pyrimidina-6(3,2)-pyridina-1(1,3)-benzenacyclodecaphane

参考文献

1. Farand J, et al. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5926-5930.

Pyk2-IN-25a

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物理化学性质&存储条件

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Pyk2-IN-25a

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