Purvalanol A (NG-60) | CDK inhibitor | Probechem Biochemicals

Chemical Structure : Purvalanol A

CAS No.: 212844-53-6

加入收藏

Purvalanol A (NG-60, NG60)

货号: PC-45447Not For Human Use, Lab Use Only.

Purvalanol A (NG-60) is a potent, cell-permeable, selective inhibitor of CDK with IC50s of 4, 70, 35, 850, and 75 nM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

规格	价格	库存
5 mg	￥680	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg	￥3280	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Purvalanol A (NG-60) is a potent, cell-permeable, selective inhibitor of CDK with IC50s of 4, 70, 35, 850, and 75 nM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.
Purvalanol A (NG-60)also inhibits Saccharomyces cerevisiae Cdc28p (IC50=80 nM) and has no effect on PKC, Raf, CK1, CK2.

物理化学性质&存储条件

分子量	388.8944
分子式	C19H25ClN6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-

参考文献

1. Gray NS, et al. Science. 1998 Jul 24;281(5376):533-8.

2. Chadebech P, et al. Int J Cancer. 2000 Sep 15;87(6):779-86.

3. Obakan P, et al. Mol Biol Rep. 2014 Jan;41(1):145-54.

Purvalanol A (NG-60, NG60)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Purvalanol A (NG-60, NG60)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.