Chemical Structure : Propofol
CAS No.: 2078-54-8
货号: PC-70280Not For Human Use, Lab Use Only.
Propofol (2,6-Diisopropylphenol) is a widely used general anesthetic to induce and maintain anesthesia, also inhibits kinesin-1 KIF5B and kinesin-2 KIF3AB and KIF3AC.
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---|---|---|---|
100 mg | ¥480 | In stock | |
250 mg | ¥780 | In stock | |
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Propofol (2,6-Diisopropylphenol) is a widely used general anesthetic to induce and maintain anesthesia, also inhibits kinesin-1 KIF5B and kinesin-2 KIF3AB and KIF3AC.
Propofol (2,6-Diisopropylphenol) influences ligand-gated channels, including the GABAA receptor and others.
Propofol (2,6-Diisopropylphenol) also inhibits conventional kinesin-1 KIF5B and kinesin-2 KIF3AB and KIF3AC, causing a significant reduction in the distances that these processive kinesins can travel without an effect on velocity (EC50<100 nM).
分子量 | 178.271 | |
分子式 | C12H18O | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Phenol, 2,6-diisopropyl- (6CI,8CI) |
1. Bensel BM, et al. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4281-E4287.
2. Jin WZ, et al. Eur J Pharmacol. 2016 Oct 5;788:37-44.
3. Eaton MM, et al. Curr Neuropharmacol. 2016;14(7):772-80.
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