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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-Procaspase-6 inhibitor 13
Procaspase-6 inhibitor 13

Chemical Structure : Procaspase-6 inhibitor 13

CAS No.: 1575392-45-8

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Procaspase-6 inhibitor 13 (Procaspase-6-IN-13)

货号: PC-73051Not For Human Use, Lab Use Only.

Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM.
    Procaspase-6 inhibitor 13 binds to pro-C6 at the dimer interface and contacts amino acids Y198, T199 and E214.
    Procaspase-6 inhibitor 13 significantly stabilizes procaspase-6.

    物理化学性质&存储条件

    分子量 311.32
    分子式 C16H14FN5O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(((3-(5-aminopyrimidin-2-yl)pyridin-2-yl)amino)methyl)-5-fluorophenol

    参考文献

    1. Jeremy Murray, et al. ChemMedChem. 2014 Jan;9(1):73-7, 2.

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