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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-ProTx II
ProTx II

Chemical Structure : ProTx II

CAS No.: 484598-36-9

ProTx II (Protoxin II)

货号: PC-72206Not For Human Use, Lab Use Only.

ProTx II (Protoxin II) is a selective NaV1.7 channel blocker with IC50 of 0.3 nM, 100-fold selectivity over other sodium channel subtypes.

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100 ug ¥2580 In stock
500 ug ¥4580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ProTx II (Protoxin II) is a selective NaV1.7 channel blocker with IC50 of 0.3 nM, 100-fold selectivity over other sodium channel subtypes.

物理化学性质&存储条件

分子量 3828
分子式 C168H250N46O41S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

Chemical Name/SMILES

Tyr-Cys2-Gln-Lys-Trp-Met-Trp-Thr-Cys9-Asp-Ser-Glu-Arg-Lys-Cys15-Cys16-Glu-Gly-Met-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Lys-Lys-Leu-Trp-OH, Cys2-Cys16, Cys9-Cys21 and Cys15-Cys25

参考文献

1. Xu H, et al. Cell. 2019 Feb 7;176(4):702-715.e14.

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