Pritelivir | Antiviral | Probechem Biochemicals

Chemical Structure : Pritelivir

CAS No.: 348086-71-5

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Pritelivir (AIC316, BAY 57-1293)

货号: PC-73147Not For Human Use, Lab Use Only.

Pritelivir (AIC316) is an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro (HSV-1 and HSV-2, IC50=0.02 uM).

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100 mg	￥2280	In stock
500 mg	￥4980	In stock
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生物&药学活性

Pritelivir (AIC316) is an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro (HSV-1 and HSV-2, IC50=0.02 uM).
Pritelivir ritelivir (0.03-45 mg/kg) significantly increases survival, reduces mortality against HSV-1, E-377.
Pritelivir has potent and resistance-breaking antiviral efficacy with potential for the treatment of potentially life-threatening HSV type 1 and 2 infections, including herpes simplex encephalitis.

物理化学性质&存储条件

分子量	402.49
分子式	C18H18N4O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide

参考文献

1. Quenelle DC, et al. Antiviral Res. 2018 Jan;149:1-6.

2. Wald A, et al. N Engl J Med. 2014 Jan 16;370(3):201-10.

3. Ligat G, et al. Front Microbiol. 2018 Oct 23;9:2483.

Pritelivir (AIC316, BAY 57-1293)

生物&药学活性

物理化学性质&存储条件

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Pritelivir (AIC316, BAY 57-1293)

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物理化学性质&存储条件

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