Presatovir |CAS:1353625-73-6 Probechem Biochemicals

Chemical Structure : Presatovir

CAS No.: 1353625-73-6

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Presatovir (GS-5806;GS5806)

货号: PC-45063Not For Human Use, Lab Use Only.

Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates.

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10 mg	￥3980	In stock
25 mg	￥6580	In stock
100 mg	￥14800	In stock
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1 g		Get quote

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生物&药学活性

Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates.
Presatovir (GS-5806) exhibits low cytotoxicity in human cell lines and primary cell cultures (selectivity > 23,000-fold).
Presatovir (GS-5806) shows excellent antiviral efficacy in the cotton rat model of RSV infection.

物理化学性质&存储条件

分子量	532.0581
分子式	C24H30ClN7O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanesulfonamide, N-[2-[[(2S)-2-[5-[(3S)-3-amino-1-pyrrolidinyl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]-1-piperidinyl]carbonyl]-4-chlorophenyl]-

参考文献

1. Mackman RL, et al. J Med Chem. 2015 Feb 26;58(4):1630-43.

2. Jordan R, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4889-900.

3. Perron M, et al. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1264-73.

Presatovir (GS-5806;GS5806)

生物&药学活性

物理化学性质&存储条件

参考文献

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Presatovir (GS-5806;GS5806)

生物&药学活性

物理化学性质&存储条件

参考文献

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