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首页-小分子抑制剂&激动剂-GPCR-Leukotriene Receptor-Pranlukast
Pranlukast

Chemical Structure : Pranlukast

CAS No.: 103177-37-3

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Pranlukast (ONO-1078, ONO1078, SB 205312)

货号: PC-23321Not For Human Use, Lab Use Only.

Pranlukast (SB 205312, ONO-1078) is a highly potent, selective and competitive leukotriene antagonist, inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Ki values of 0.63 nM, 0.99 nM, and 5640 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pranlukast (SB 205312, ONO-1078) is a highly potent, selective and competitive leukotriene antagonist, inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Ki values of 0.63 nM, 0.99 nM, and 5640 nM, respectively.

物理化学性质&存储条件

分子量 481.51
分子式 C27H23N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl)-4-(4-phenylbutoxy)benzamide

参考文献

1. Torii T, et al. Heart Vessels. 1988;4(2):104-11.

2. Fujiwara H, et al. Prostaglandins Leukot Essent Fatty Acids. 1993 Mar;48(3):241-6.

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