Chemical Structure : Pralatrexate
CAS No.: 146464-95-1
货号: PC-42590Not For Human Use, Lab Use Only.
Pralatrexate is a potent dihydrofolate reductasean (DHFR) inhibitor with Ki of 13.4 pM, is an antifolate and has antitumor activities.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | ¥980 | In stock | |
| 25 mg | ¥1580 | In stock | |
| 50 mg | ¥2580 | In stock | |
| 100 mg | Get quote |
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Pralatrexate is a potent dihydrofolate reductasean (DHFR) inhibitor with Ki of 13.4 pM, is an antifolate and has antitumor activities.
| 分子量 | 477.4726 | |
| 分子式 | C23H23N7O5 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]- |
|
1. DeGraw JI, et al. J Med Chem. 1993 Jul 23;36(15):2228-31.
2. Krug LM, et al. Clin Cancer Res. 2000 Sep;6(9):3493-8.
3. Wang ES, et al. Leuk Lymphoma. 2003 Jun;44(6):1027-35.
4. Molina JR. IDrugs. 2008 Jul;11(7):508-21.
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