Pralatrexate |CAS:146464-95-1 Probechem Biochemicals

Chemical Structure : Pralatrexate

CAS No.: 146464-95-1

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货号: PC-42590Not For Human Use, Lab Use Only.

An antifolate that fuctions as a dihydrofolate reductase inhibitor for treatment of several malignancies..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An antifolate that fuctions as a dihydrofolate reductase inhibitor for treatment of several malignancies.

Chemotherapeutic Agents

Approved

分子量	477.4726
分子式	C23H23N7O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-

1. DeGraw JI, et al. J Med Chem. 1993 Jul 23;36(15):2228-31.

2. Krug LM, et al. Clin Cancer Res. 2000 Sep;6(9):3493-8.

3. Wang ES, et al. Leuk Lymphoma. 2003 Jun;44(6):1027-35.

4. Molina JR. IDrugs. 2008 Jul;11(7):508-21.

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