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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-PrNMI
PrNMI

Chemical Structure : PrNMI

CAS No.: 1541244-33-0

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PrNMI

货号: PC-35125Not For Human Use, Lab Use Only.

PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist with Ki of 1.18 nM and EC50 of 182 nM (hCB1R).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist with Ki of 1.18 nM and EC50 of 182 nM (hCB1R).
PrNMI significantly alleviates spontaneous pain behaviors in animals.

物理化学性质&存储条件

分子量 409.573
分子式 C29H31NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-{2-[-(1E)-1[(4-propylnaphthalen-1-yl)methylidene]-1H-inden-3-yl]ethyl}morpholine

参考文献

1. Zhang H, et al. Pain. 2018 May 16. doi: 10.1097/j.pain.0000000000001278.
2. Herbert H Seltzman, et al. J Med Chem. 2016 Aug 25;59(16):7525-43.

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