欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Others-Other Targets-Polyphyllin VI
Polyphyllin VI

Chemical Structure : Polyphyllin VI

CAS No.: 55916-51-3

加入收藏

Polyphyllin VI (PP-VI, PPVI)

货号: PC-27529Not For Human Use, Lab Use Only.

Polyphyllin VI (PP-VI, PPVI) is a steroidal saponin isolated from Paris polyphylla with broad and strong anticancer effect and anti-metastatic activity, increases expression of Rell2 (Receptor expressed in lymphoid tissue (RELT)-like 2) and decreases level of miR-18a in 4T1 and MDA-MB-231 cells.

规格 价格 库存 数量
5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Polyphyllin VI (PP-VI, PPVI) is a steroidal saponin isolated from Paris polyphylla with broad and strong anticancer effect and anti-metastatic activity, increases expression of Rell2 (Receptor expressed in lymphoid tissue (RELT)-like 2) and decreases level of miR-18a in 4T1 and MDA-MB-231 cells.
Polyphyllin VI impaires the viability of 4T1 and MDA-MB-231 cells.
Polyphyllin VI suppresses the metastatic potential of 4T1 and MDA-MB-231 cells.
Polyphyllin VI attenuates miR-18a mimic or Rell2 siRNA-augmented migration of MDA-MB-231 cells.
Polyphyllin VI inhibits the proliferation of glioma cell lines by modulating the G2/M phase, promotes apoptosis, autophagy, increases accumulation of ROS and activates ROS-modulated JNK and p38 pathways.
Polyphyllin VI inhibited tumor growth of U87 cell line in nude mice.

物理化学性质&存储条件

分子量 738.90
分子式 C39H62O13
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-

参考文献

1. Yin X, et al. Biomed Chromatogr. 2013 Mar;27(3):343-8.

2. Wang P, et al. Eur J Pharmacol. 2019 May 15;851:161-173.

3. Liu W, et al. Onco Targets Ther. 2020 Mar 13;13:2275-2288.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: