Chemical Structure : Polatuzumab
CAS No.: 1313206-42-6
货号: PC-Ab1112Not For Human Use, Lab Use Only.
Polatuzumab (Anti-human CD79b) is a human CD79b mAb, component of antibody-drug conjugate (ADC) Polatuzumab vedotin. Polatuzumab is internalized, cleaved by lysosomal proteases, thereby delivering MMAE to malignant B-cells. The released MMAE binds to microtubules and kills dividing cells by inhibiting cell division and inducing apoptosis. CD79B is a subunit of the heterodimer B-cell receptor Igα/Igβ (CD79A/CD79B), also known as B29, Ig beta and B cell antigen receptor complex-associated protein
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Polatuzumab (Anti-human CD79b) is a human CD79b mAb, component of antibody-drug conjugate (ADC) Polatuzumab vedotin. Polatuzumab is internalized, cleaved by lysosomal proteases, thereby delivering MMAE to malignant B-cells. The released MMAE binds to microtubules and kills dividing cells by inhibiting cell division and inducing apoptosis. CD79B is a subunit of the heterodimer B-cell receptor Igα/Igβ (CD79A/CD79B), also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
|
Chemical Name/SMILES |
Polatuzumab; Anti-human CD79b; Anti-human B-cell receptor Igβ; 1313206-42-6 |
1. 1, Sehn LH, et al. J Clin Oncol. 2020 Jan 10;38(2):155-165. 2, Bourbon E, et al. Expert Opin Investig Drugs. 2020 Oct;29(10):1079-1088. 3, Tilly H, et al. Lancet Oncol. 2019 Jul;20(7):998-1010. 4, Segman Y, et al. Leuk Lymphoma. 2021 Jan;62(1):118-124.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright