Plerixafor octahydrochloride (JM-3100, AMD3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10 ng/ml.
Plerixafor octahydrochloride (JM-3100, AMD3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10 ng/ml.
Plerixafor octahydrochloride (JM-3100, AMD3100) can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF.
Plerixafor octahydrochloride (JM-3100, AMD3100) also is an allosteric agonist of CXCR7.
