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Pleconaril

Chemical Structure : Pleconaril

CAS No.: 153168-05-9

Pleconaril (Picovir;VP-63843;Win-63843)

货号: PC-45760Not For Human Use, Lab Use Only.

Pleconaril (Picovir, VP-63843, Win-63843) is a broad spectrum antipicornaviral agent that inhibits rhinovirus replication by interaction with the VP1 protein.

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50 mg ¥3600 In stock
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500 mg ¥10800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pleconaril (Picovir, VP-63843, Win-63843) is a broad spectrum antipicornaviral agent that inhibits rhinovirus replication by interaction with the VP1 protein; inhibits EV-D68 with EC50 of 430 nM; shows active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.

Rhinovirus Infection

Phase 2 Clinical

物理化学性质&存储条件

分子量 381.349
分子式 C18H18F3N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,2,4-Oxadiazole, 3-[3,5-dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-

参考文献

1. Florea NR, et al. Pharmacotherapy. 2003 Mar;23(3):339-48.

2. Pevear DC, et al. Antimicrob Agents Chemother. 1999 Sep;43(9):2109-15.

3. Liu Y, et al. Science. 2015 Jan 2;347(6217):71-4.

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