Pinosylvin

Chemical Structure : Pinosylvin

CAS No.: 22139-77-1

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货号: PC-24833Not For Human Use, Lab Use Only.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg		Get quote

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生物&药学活性

Pinosylvin is a naturally occurring molecule traditionally found in pinus trees with antibacterial, antifungal and anticancer activity, shows potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae.
Pinosylvin selectively inhibits LPS- and RANKL-induced release of IL-1beta effectively reducing osteoclastogenesis.
Pinosylvin significantly inhibits the release of pro-inflammatory cytokines (TNF-α and IL-6) and NO mediator in LPS-stimulated RAW 264.7 cells.
Pinosylvin showed its anti-inflammatory activity by inhibiting the PGE2 production mediated by COX-2 in RAW 264.7 cells treated with LPS (1 µg/mL) with an IC50 value of 10.6 µM.
Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial-mesenchymal transition and inhibition of MMP-2.

物理化学性质&存储条件

分子量	212.25
分子式	C14H12O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	trans-3,5-dihydroxystilbene

参考文献

1. Perri MR, et al. Pharmaceuticals (Basel). 2023 May 9;16(5):718.

2. Zhang W, et al. Adv Sci (Weinh). 2025 Jun 10:e01532.

3. Chuang YC, et al. Oncol Rep. 2021 Jul;46(1):143. doi: 10.3892/or.2021.8094.

Pinosylvin

生物&药学活性

物理化学性质&存储条件

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Pinosylvin

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