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首页-小分子抑制剂&激动剂-Others-Other Targets-Pinoresinol
Pinoresinol

Chemical Structure : Pinoresinol

CAS No.: 487-36-5

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Pinoresinol ((+)-Pinoresinol)

货号: PC-27917Not For Human Use, Lab Use Only.

Pinoresinol ((+)-Pinoresinol) is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds, shows inhibitory activity against rat intestinal α-glucosidase with IC50 of 34.3 uM, inhibits proliferation and induces differentiation on human HL60 leukemia cells, also exerts enzymatic β-glucuronidase inhibitory activity with IC50 of 27.9 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pinoresinol ((+)-Pinoresinol) is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds, shows inhibitory activity against rat intestinal α-glucosidase with IC50 of 34.3 uM, inhibits proliferation and induces differentiation on human HL60 leukemia cells, also exerts enzymatic β-glucuronidase inhibitory activity with IC50 of 27.9 uM.

物理化学性质&存储条件

分子量 358.39
分子式 C20H22O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,4'-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol)

参考文献

1. Chen CC, et al. Planta Med. 1999 Dec;65(8):709-11.

2. Wikul A, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5215-7.

3. Wang GK, et al. Nat Prod Res. 2013 Aug;27(15):1348-52.

4. Nishikawa S, et al. J Nat Med. 2026 Jul 28. doi: 10.1007/s11418-026-02070-1.

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