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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Pinacidil
Pinacidil

Chemical Structure : Pinacidil

CAS No.: 60560-33-0

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Pinacidil (P-1134, P1134)

货号: PC-21737Not For Human Use, Lab Use Only.

Pinacidil (P-1134) is a potent activator of potassium channel, hyperpolarises vascular smooth muscle by opening K+-channels, significantly improves the reperfusion function and cardiac compliance and has direct cardioprotective efficacy.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pinacidil (P-1134) is a potent activator of potassium channel, hyperpolarises vascular smooth muscle by opening K+-channels, significantly improves the reperfusion function and cardiac compliance and has direct cardioprotective efficacy.

物理化学性质&存储条件

分子量 245.33
分子式 C13H19N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3,3-Dimethylbutan-2-yl)-2-cyano-3-(pyridin-4-yl)guanidine

参考文献

1. Grover GJ, et al. J Pharmacol Exp Ther. 1989;251(1):98-104.

2. Hamilton TC, et al. Gen Pharmacol. 1989;20(1):1-9.

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