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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-Pifithrin-α hydrobromide
Pifithrin-α hydrobromide

Chemical Structure : Pifithrin-α hydrobromide

CAS No.: 63208-82-2

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Pifithrin-α hydrobromide (Pifithrin hydrobromide, PFTα hydrobromide)

货号: PC-22247Not For Human Use, Lab Use Only.

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

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5 mg ￥580 In stock
10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pifithrin-α hydrobromide is a small molecule inhibitor of p53, blocks its transcriptional activity and prevents cells from apoptosis, also is an aryl hydrocarbon receptor (AhR) agonist.

物理化学性质&存储条件

分子量 367.31
分子式 C16H19BrN2OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide

参考文献

1. Yu W, et al. Int J Biol Sci. 2016 Jan 1;12(2):198-209.

2. Hoagland MS, et al. J Pharmacol Exp Ther. 2005 Aug;314(2):603-10.

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