Piericidin A | Complex I inhibitor | Probechem Biochemicals

Chemical Structure : Piericidin A

CAS No.: 2738-64-9

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Piericidin A (AR-054)

货号: PC-20782Not For Human Use, Lab Use Only.

Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor.

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5 mg	￥7980	In stock
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生物&药学活性

Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor.
Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase.
Piericidin A is a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca).

物理化学性质&存储条件

分子量	415.57
分子式	C25H37NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Bridges HR, et al. Nat Commun. 2020 Oct 16;11(1):5261.

2. Baradaran R, et al. Nature. 2013;494:443–448.

3. Horgan DJ, et al. J. Biol. Chem. 1968;243:5967–5976.

4. i Eun Kang, et al. Microbiol Res. 2016 Mar;18

Piericidin A (AR-054)

生物&药学活性

物理化学性质&存储条件

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Piericidin A (AR-054)

生物&药学活性

物理化学性质&存储条件

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