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首页-小分子抑制剂&激动剂-TGF-beta/Smad-PKC-Phorbol 12-myristate 13-acetate
Phorbol 12-myristate 13-acetate

Chemical Structure : Phorbol 12-myristate 13-acetate

CAS No.: 16561-29-8

Phorbol 12-myristate 13-acetate (PMA)

货号: PC-45546Not For Human Use, Lab Use Only.

Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.

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5 mg ¥1280 In stock
10 mg ¥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Phorbol 12-myristate 13-acetate (PMA) is a PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.
Phorbol 12-myristate 13-acetate (PMA) is a potent tumor promoter often employed in biomedical research.

物理化学性质&存储条件

分子量 616.825
分子式 C36H56O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 62 mg/mL

Chemical Name/SMILES

Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester

参考文献

1. Xu F, et al. Br J Pharmacol. 2003 Sep;140(2):413-21.

2. Blumberg PM, et al. Cancer Res. 1988 Jan 1;48(1):1-8.

3. Niedel JE, et al. Proc Natl Acad Sci U S A. 1983 Jan;80(1):36-40.

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