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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-PhiKan083
PhiKan083

Chemical Structure : PhiKan083

CAS No.: 880813-36-5

PhiKan083 (PhiKan-083, PhiKan 083)

货号: PC-25767Not For Human Use, Lab Use Only.

PhiKan083 (PhiKan 083) is a specific reactivator and stabilizer and reactivator of p53 Y220C mutant with dissociation constant of 150 uM, binds to the surface cavity and stabilizes p53 Y220C..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PhiKan083 (PhiKan 083) is a specific reactivator and stabilizer and reactivator of p53 Y220C mutant with dissociation constant of 150 uM, binds to the surface cavity and stabilizes p53 Y220C.

物理化学性质&存储条件

分子量 238.33
分子式 C16H18N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(9-Ethyl-9H-carbazol-3-yl)-N-methylmethanamine

参考文献

1. Boeckler FM, et al. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5.

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