Phenamil methanesulfonate

Chemical Structure : Phenamil methanesulfonate

CAS No.: 1161-94-0

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货号: PC-23761Not For Human Use, Lab Use Only.

Phenamil methanesulfonate is a potent, reversible epithelial sodium channel (ENaC) blocker with IC50 of 400 nM, is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with IC50 of 140 nM in Ca2+ uptake assay.

规格	价格	库存
5 mg	￥1480	In stock
10 mg	￥2180	In stock
25 mg	￥3780	In stock
50 mg		Get quote
100 mg		Get quote

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物理化学性质&存储条件

分子量	401.83
分子式	C13H16ClN7O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-Diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide methanesulfonate

参考文献

1. Xiao-Qing Dai , et al. Mol Pharmacol. . 2007 Dec;72(6):1576-85.

2. Andrew J Hirsh, et al. J Med Chem. 2006 Jul 13;49(14):4098-115.