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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Pezulepistat
Pezulepistat

Chemical Structure : Pezulepistat

CAS No.: 2562303-35-7

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Pezulepistat

货号: PC-25078Not For Human Use, Lab Use Only.

Pezulepistat (Compound II) is a potent, selective inhibitor of bacterial type 1 signal peptidase LepB, shows serum MIC value of 0.5 μM against E. coli 25922, exhibits broad spectrum antibiotic activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Pezulepistat (Compound II) is a potent, selective inhibitor of bacterial type 1 signal peptidase LepB, shows serum MIC value of 0.5 μM against E. coli 25922, exhibits broad spectrum antibiotic activity.

物理化学性质&存储条件

分子量 1008.12
分子式 C46H61N11O13S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

OC1=C2C3=C(OC[C@@H](CN)O)C=CC(=C3)C[C@@H](C(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N(C([C@@H](NC(=O)C=4C(C)=NC(=NC4N)C5=CC=C(C(C)(C)C)C=C5)CNS(N)(=O)=O)=O)C)C(=C2)C=C1OC[C@@H](CN)O

参考文献

1. Patent WO2020243155 A1.

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