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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HBV-Pevifoscorvir
Pevifoscorvir

Chemical Structure : Pevifoscorvir

CAS No.: 2495324-71-3

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Pevifoscorvir (ALG-000184 free base)

货号: PC-27491Not For Human Use, Lab Use Only.

Pevifoscorvir (ALG-000184 free base) is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Pevifoscorvir (ALG-000184 free base) is a highly soluble prodrug of the potent HBV capsid assembly modulator (CAM) ALG-001075 (HepG2.117, EC50=0.63 nM).

物理化学性质&存储条件

分子量 532.42
分子式 C23H22FN4O8P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Pyrrole-3-acetamide, 5-[[(3-cyano-4-fluorophenyl)amino]carbonyl]-N-(3-ethynyl-3-oxetanyl)-1,2,4-trimethyl-α-oxo-N-[(phosphonooxy)methyl]-

参考文献

1. Vendeville S, et al. J Med Chem. 2024 Dec 12;67(23):21126-21142.

2. Gane E, et al. Antivir Ther. 2025 Dec;30(6):13596535251392955.

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