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首页-小分子抑制剂&激动剂-GPCR-Amylin receptor (AMYR)-Petrelintide acetate
Petrelintide acetate

Chemical Structure : Petrelintide acetate

CAS No.:

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Petrelintide acetate (ZP8396 acetate)

货号: PC-27451Not For Human Use, Lab Use Only.

Petrelintide acetate (ZP8396 acetate) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

规格 价格 库存 数量
2 mg ￥2480 In stock
5 mg ￥3980 In stock
10 mg ￥5880 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Petrelintide acetate (ZP8396 acetate) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

物理化学性质&存储条件

分子量 4191.69 (free base)
分子式 C185H305N49O61.xC2H4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

{γGlu-arachidate}-Arg-Asp-Gly-Thr-Ala-Thr-Lys-Ala-Thr-Glu-Arg-Leu-Ala-{homoGlu}-Phe-Leu-Gln-Arg-Ser-Ser-Phe-{Sar}-Ala{NMeIle}-Leu-Ser-Ser-Thr-Glu-Val-Gly-Ser-Asn-Thr-{Hyp}-NH2 (Lactm bridge:Asp3-Lys8) acetate salt

参考文献

1. Fischer Munch H, et al. J Med Chem. 2025 Nov 27;68(22):23925-23940.

2. Brændholt Olsen M, et al. Diabetes Obes Metab. 2026 Jul;28(7):5915-5925.

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