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首页-抗体和重组蛋白-Biosimilar Antibody-Pertuzumab
Pertuzumab

Chemical Structure : Pertuzumab

CAS No.: 380610-27-5

Pertuzumab (Anti-human HER2 mAb, human IgG1-Kappa; Omnitarg, 2C4)

货号: PC-Ab1064Not For Human Use, Lab Use Only.

Pertuzumab is a recombinant humanized monoclonal antibody that binds to the extracellular dimerization domain II of HER2 and inhibits heterodimerization of HER2 with other HER family members, including EGF receptor (EGFR), HER3, and HER4..

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5 mg ¥7580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pertuzumab is a recombinant humanized monoclonal antibody that binds to the extracellular dimerization domain II of HER2 and inhibits heterodimerization of HER2 with other HER family members, including EGF receptor (EGFR), HER3, and HER4.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Pertuzumab; Perjeta; 380610-27-5; HER2; ERBB2; erb-b2 receptor tyrosine kinase 2; human epidermal growth factor receptor 2; EGFR2; Omnitarg, 2C4

参考文献

1. 1, Swain SM, et al. N Engl J Med. 2015 Feb 19;372(8):724-34. 2, Gianni L, et al. Lancet Oncol. 2012 Jan;13(1):25-32. 3, Franklin MC, et al. Cancer Cell. 2004 Apr;5(4):317-28. 4, Nahta R, et al. Cancer Res. 2004 Apr 1;64(7):2343-6. 5, Badache A, et al. Cancer Cell. 2004 Apr;5(4):299-301.

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