Chemical Structure : Pembrolizumab
CAS No.: 1374853-91-4
货号: PC-Ab1031Not For Human Use, Lab Use Only.
Pembrolizumab was the first anti-PD-1 antibody to be approved by the US Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma with disease progression following ipilimumab, and if BRAF (V600) mutation positive, a BRAF inhibitor. Pembrolizumab has also received breakthrough status for the treatment of EGFR mutation-negative, ALK rearrangement-negative non-small cell lung cancer (NSCLC) that has progressed on or following platinum-based chemotherapy. .
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Pembrolizumab was the first anti-PD-1 antibody to be approved by the US Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma with disease progression following ipilimumab, and if BRAF (V600) mutation positive, a BRAF inhibitor. Pembrolizumab has also received breakthrough status for the treatment of EGFR mutation-negative, ALK rearrangement-negative non-small cell lung cancer (NSCLC) that has progressed on or following platinum-based chemotherapy.
分子量 | ||
分子式 | Human IgG4 (S228P)-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Pembrolizumab; Keytruda; MK3475; MK-3475; MK 3475; CD279; programmed death-1; programmed death 1 ; PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1 |
1. 1, Robert C, et al. N Engl J Med. 2015 Jun 25;372(26):2521-32. 2, Herbst RS, et al. Lancet. 2016 Apr 9;387(10027):1540-1550. 3, Tumeh PC, et al. Nature. 2014 Nov 27;515(7528):568-71. 4, Hamid O, et al. N Engl J Med. 2013 Jul 11;369(2):134-44.
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