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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate

Chemical Structure : Paroxetine hydrochloride hemihydrate

CAS No.: 110429-35-1

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Paroxetine hydrochloride hemihydrate (BRL29060 hydrochloride hemihydrate;BRL29060A hemihydrate)

货号: PC-46650Not For Human Use, Lab Use Only.

An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

规格 价格 库存 数量
500 mg ￥1200 In stock
1 g ￥1950 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells; induce autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder.

Depression

Approved

物理化学性质&存储条件

分子量 374.83
分子式 C19H22ClFNO3.5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:2:1), (3S,4R)-

参考文献

1. Thal DM, et al. ACS Chem Biol. 2012 Nov 16;7(11):1830-9.

2. Gassen NC, et al. Autophagy. 2015;11(3):578-80.

3. Alcocer-Gómez E, et al. Pharmacol Res. 2017 Jul;121:114-121.

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