Pannexin-1 inhibitor 15b | Pannexin-1 inhibitor | Probechem Biochemicals

Chemical Structure : Pannexin-1 inhibitor 15b

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Pannexin-1 inhibitor 15b (Pannexin-1 inhibitor)

货号: PC-72399Not For Human Use, Lab Use Only.

Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.

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100 mg		Get quote
250 mg		Get quote

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生物&药学活性

Pannexin-1 inhibitor 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.
Pannexin-1 inhibitor 15b (administered intrathecally, 1 nM) completely reverted the hypersensitivity in the mouse model of oxaliplatin-induced neuropa.

物理化学性质&存储条件

分子量	508.501
分子式	C25H20N2O8S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-Carboxybenzyl)-5-(N-(4-carboxybenzyl)sulfamoyl)-1Hindole-2-carboxylic acid

参考文献

1. Letizia Crocetti, et al. Eur J Med Chem. 2021 Nov 5;223:113650.