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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-Palonosetron hydrochloride
Palonosetron hydrochloride

Chemical Structure : Palonosetron hydrochloride

CAS No.: 135729-62-3

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Palonosetron hydrochloride (RS 25259-197)

货号: PC-24876Not For Human Use, Lab Use Only.

Palonosetron (RS 25259-197) is a potent, selective 5-HT3 receptor antagonist with pKi value of 10.4, >10,000-fold selective over 5-HT1A/1D/2A/2C receptors.

规格 价格 库存 数量
50 mg ￥480 In stock
100 mg ￥780 In stock
250 mg ￥1280 In stock
1 g Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Palonosetron (RS 25259-197) is a potent, selective 5-HT3 receptor antagonist with pKi value of 10.4, >10,000-fold selective over 5-HT1A/1D/2A/2C receptors.

物理化学性质&存储条件

分子量 332.87
分子式 C19H25ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride

参考文献

1. Clark RD, et al. J Med Chem. 1993 Sep 3;36(18):2645-57.

2. Wong EH, et al. Br J Pharmacol. 1995 Feb;114(4):851-9.

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