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首页-抗体和重组蛋白-Biosimilar Antibody-Pacanalotamab
Pacanalotamab

Chemical Structure : Pacanalotamab

CAS No.: 2251756-52-0

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Pacanalotamab (AMG420)

货号: PC-38863Not For Human Use, Lab Use Only.

Pacanalotamab (AMG420) is a bispecific T-cell engager (BiTE) antibody, binds BCMA (B-Cell Maturation Antigen) on MM cells and CD3 on T cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Pacanalotamab (AMG420) is a bispecific T-cell engager (BiTE) antibody, binds BCMA (B-Cell Maturation Antigen) on MM cells and CD3 on T cells.

Isotype: Immunoglobulin scFv-scFv.

Anti-[human TNFRSF17 (TNF receptor superfamily member 17, tumor necrosis factor receptor superfamily, member 17, B cell maturation antigen, BCMA, BCM, TNFRSF13A, CD269)] and anti- [human CD3E (CD3 epsilon)], monoclonal antibody single chain, bispecific.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Verkleij CPM, et al. Oncotarget. 2020 Nov 10;11(45):4076-4081.

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