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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-PW0464
PW0464

Chemical Structure : PW0464

CAS No.: 1643462-93-4

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PW0464 ((Rac)-Razpipadon)

货号: PC-23108Not For Human Use, Lab Use Only.

PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%.

物理化学性质&存储条件

分子量 389.36
分子式 C19H17F2N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,4(1H,3H)-Pyrimidinedione, 6-[4-[[3-(difluoromethoxy)-2-pyridinyl]oxy]-2-methylphenyl]-1,5-dimethyl-

参考文献

1. Wang P, et al. ACS Med Chem Lett. 2019 Apr 5;10(5):792-799.

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