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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Checkpoint Kinase (Chk)-PV-1115
PV-1115

Chemical Structure : PV-1115

CAS No.: 1093793-10-2

PV-1115 (PV 1115;PV1115)

货号: PC-60284Not For Human Use, Lab Use Only.

PV-1115 (PV1115) is a potent and highly selective Chk2 inhibitor with IC50 of 0.14 nM, displays greater than 100 uM for Chk1 in vitro.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PV-1115 (PV1115) is a potent and highly selective Chk2 inhibitor with IC50 of 0.14 nM, displays greater than 100 uM for Chk1 in vitro.

    物理化学性质&存储条件

    分子量 405.418
    分子式 C20H19N7O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-(1-(2-(4,5-dihydro-1H-imidazol-2-yl)hydrazono)ethyl)phenyl)-7-nitro-1H-indole-2-carboxamide

    参考文献

    1. Lountos GT, et al. J Struct Biol. 2011 Dec; 176(3):292-301.

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