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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-PUC-55
PUC-55

Chemical Structure : PUC-55

CAS No.:

PUC-55

货号: PC-24221Not For Human Use, Lab Use Only.

PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=37.5 nM), induces autophagy in the neuroblastoma SH-SY5Y cell line by inhibiting the mTOR pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=37.5 nM), induces autophagy in the neuroblastoma SH-SY5Y cell line by inhibiting the mTOR pathway.

物理化学性质&存储条件

分子量 542.65
分子式 C30H30N4O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(1-(naphthalen-1-ylsulfonyl)-1H-indazol-3-yl)ethan-1-ol

参考文献

1. Alcaíno JM, et al. Sci Rep. 2025 Mar 11;15(1):8380. doi: 10.1038/s41598-025-92755-6.

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