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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-PU-WS13
PU-WS13

Chemical Structure : PU-WS13

CAS No.: 1454619-14-7

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PU-WS13 (PU-WS-13)

货号: PC-45521Not For Human Use, Lab Use Only.

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.

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10 mg ￥1580 In stock
25 mg ￥2780 In stock
50 mg ￥4580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PU-WS13 is a potent and selective Grp94 inhibitor with IC50 of 0.22 uM.
PU-WS13 shows >35 fold selectivity over other four HSP90 paralogs, Hsp90α, Hsp90β and Trap-1 (IC50> 7 uM).

物理化学性质&存储条件

分子量 411.3519
分子式 C17H20Cl2N6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-

参考文献

1. Patel PD, et al. Nat Chem Biol. 2013 Nov;9(11):677-84.

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