PTK7/β-catenin inhibitor 01065

Chemical Structure : PTK7/β-catenin inhibitor 01065

CAS No.: 906147-24-8

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货号: PC-38652Not For Human Use, Lab Use Only.

PTK7/β-catenin inhibitor 01065 is a small molecule inhibitor of PTK7/β-catenin interaction (IC50=8.9 uM) targeting the Wnt pathway signaling, induces antiproliferative and antitumor effects in vitro in CRC cells harboring β-catenin or adenomatous polyposis coli (APC) mutations.

规格	价格	库存
5 mg	￥3580	In stock
10 mg	￥5480	In stock
50 mg		Get quote
100 mg		Get quote

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PTK7/β-catenin inhibitor 01065 is a small molecule inhibitor of PTK7/β-catenin interaction (IC50=8.9 uM) targeting the Wnt pathway signaling, induces antiproliferative and antitumor effects in vitro in CRC cells harboring β-catenin or adenomatous polyposis coli (APC) mutations.

物理化学性质&存储条件

分子量	340.382
分子式	C22H16N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-([1,1'-biphenyl]-2-yl)-2-(1H-indol-3-yl)-2-oxoacetamide

参考文献

1. Ganier L, et al. ACS Chem Biol. 2022 Apr 28. doi: 10.1021/acschembio.1c00826.