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PTGR2 inhibitor 22

Chemical Structure : PTGR2 inhibitor 22

CAS No.: 349093-44-3

PTGR2 inhibitor 22 (PTGR2-IN-22)

货号: PC-62692Not For Human Use, Lab Use Only.

PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells.
PTGR2-IN-22 also produces a concentration-dependent rescue of 15-keto-PGE2-dependent PPARγ transcriptional activity in cells recombinantly expressing PTGR2.

物理化学性质&存储条件

分子量 310.397
分子式 C19H22N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-phenylethan-1-one

参考文献

1. Parker CG, et al. Cell. 2017 Jan 26;168(3):527-541.e29.

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