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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Microtubule/Tubulin-PTA-1
PTA-1

Chemical Structure : PTA-1

CAS No.: 1185699-58-4

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PTA-1

货号: PC-22831Not For Human Use, Lab Use Only.

PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest.

物理化学性质&存储条件

分子量 380.33
分子式 C16H15F3N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-{4-[4-methoxy-3-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl}-N-(2-methyl-2H-1,2,3-triazol-4-yl) acetamide

参考文献

1. Borrego EA, et al. Cells. 2024 Jul 20;13(14):1225.

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