PSF-RNA inhibitor C-65 | PSF-RNA inhibitor | Probechem Biochemicals

Chemical Structure : PSF-RNA inhibitor C-65

加入收藏

PSF-RNA inhibitor C-65 (PSF-RNA inhibitor)

货号: PC-20946Not For Human Use, Lab Use Only.

PSF-RNA inhibitor C-65 is a small molecule inhibitor of RNA-binding protein PSF and its target RNA with IC50 of 0.02 uM in pull-down assays.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

PSF-RNA inhibitor C-65 is a small molecule inhibitor of RNA-binding protein PSF and its target RNA with IC50 of 0.02 uM in pull-down assays.
PSF-RNA inhibitor C-65 induced apoptosis and inhibited cell growth in prostate and breast cancer cells.
PSF-RNA inhibitor C-65 up-regulated signals that are repressed by PSF, such as the cell cycle signals by p53 and p27.
PSF-RNA inhibitor C-65 significantly suppressed tumor growth and downstream target gene expression, such as the androgen receptor (AR) in mouse xenograft model for hormone therapy-resistant prostate cancer.

物理化学性质&存储条件

分子量	370.43
分子式	C18H18N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	isopropyl 4-(2-((3H-imidazo[4,5-b]pyridin-2-yl)thio)acetamido)benzoate

参考文献

1. Takayama KI, et al. PNAS Nexus. 2023 Jun 21;2(6):pgad203.