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首页-小分子抑制剂&激动剂-GPCR-GPR55-PSB-SB-487
PSB-SB-487

Chemical Structure : PSB-SB-487

CAS No.: 1399049-81-0

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PSB-SB-487 (GPR55 antagonist)

货号: PC-38506Not For Human Use, Lab Use Only.

PSB-SB-487 is a potent, selective antagonist of orphan G-protein-coupled receptor GPR55 with IC50 value 113 nM, and KB value 561 nM (hGPR55), shows little to no activity against CB1/CB2 and GPR18 receptors.

规格 价格 库存 数量
5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3780 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PSB-SB-487 is a potent, selective antagonist of orphan G-protein-coupled receptor GPR55 with IC50 value 113 nM, and KB value 561 nM (hGPR55), shows little to no activity against CB1/CB2 and GPR18 receptors.

物理化学性质&存储条件

分子量 408.538
分子式 C26H32O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-hydroxy-3-(2-hydroxybenzyl)-7-(2-methylnonan-2-yl)-2H-chromen-2-one

参考文献

1. Viktor Rempel, et al. J Med Chem. 2013 Jun 13;56(11):4798-810.

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