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首页-小分子抑制剂&激动剂-GPCR-GPR84-PSB-16434
PSB-16434

Chemical Structure : PSB-16434

CAS No.: 2189700-02-3

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PSB-16434 (PSB16434)

货号: PC-21649Not For Human Use, Lab Use Only.

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.
PSB-16434 shows selectivity over other free fatty acid-activated receptors.

物理化学性质&存储条件

分子量 265.70
分子式 C12H12ClN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-((4-chlorophenethyl)amino)pyrimidine-2,4(1H,3H)-dione

参考文献

1. Thanigaimalai Pillaiyar, et al. ACS Omega. 2018 Mar 31;3(3):3365-3383.

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