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首页-小分子抑制剂&激动剂-TGF-beta/Smad-PKC-PS428
PS428

Chemical Structure : PS428

CAS No.:

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PS428 (PS-428)

货号: PC-22772Not For Human Use, Lab Use Only.

PS428 is a small molecule, allosteric inhibitor of protein kinase C-related kinase 2 (PKN2/PRK2), binds to the PIF-pocket of PRK2 and allosterically inhibits activated PRK2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PS428 is a small molecule, allosteric inhibitor of protein kinase C-related kinase 2 (PKN2/PRK2), binds to the PIF-pocket of PRK2 and allosterically inhibits activated PRK2.

物理化学性质&存储条件

分子量 505.50
分子式 C25H19N3O7S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
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Solubility

10 mM in DMSO
Chemical Name/SMILES

ethyl 4-hydroxy-1-(6-methylbenzo[d]thiazol-2-yl)-2-(5-(3-nitrophenyl)furan-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate

参考文献

1. Gross LZF, et al. J Biol Chem. 2024 Jul 11:107550.

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